Parameters estimation in workers exposed to radioactive isotopes using multi-response models

Parameters estimation in workers exposed to radioactive isotopes using multi-response models

The metabolism of the radioactive substance intake by people can be modelled using systems of linear differential equations. Bioassays (e. g. isotopic activity excreted via urine, activity retained in the whole body or in the lungs) are applied in order to get information about some parameters of the model. In some cases, it could be convenient to use different types of bioassays in the same person, which allows better estimations of the parameters that characterize the solution of the system of equations, and in fact, sometimes it is the only practical way to get