Publicaciones

2024

1. Beyond T2-asthma biomarkers: risk stratification for NSAID-Exacerbated Respiratory Disease. ERJ Open Research 2024; Vol 10 Issue 2

2023

1. Correspondence regarding the paper “Laorden D, Zamarrón E, Romero D, Domínguez-Ortega J, Villamañán E, Losantos I, Gayá F, Quirce S, Álvarez-Sala R. Evaluation of FEOS score and super-responder criteria in a real-life cohort treated with anti-IL5/IL5R. Respir. Med. 2023; 211: 107216” Respiratory Medicine
2. Interleukin 5 Receptor Subunit Alpha Expression as a Potential Biomarker in Patients with Nasal Polyposis Biomedicines, Vol. 11, Núm. 7
3. Quantitative and qualitative methods of evaluating response to biologics in severe asthma patients: Results from a real-world study Journal of Allergy and Clinical Immunology: In Practice, Vol. 11, Núm. 3, pp. 949-951.e2
4. RNY3 modulates cell proliferation and IL13 mRNA levels in a T lymphocyte model: a possible new epigenetic mechanism of IL-13 regulation Journal of Physiology and Biochemistry, Vol. 79, Núm. 1, pp. 59-69
5. Transcriptomics reveals new regulatory mechanisms involved in benralizumab response Allergy: European Journal of Allergy and Clinical Immunology

2022

1. Editorial: Light Regulation of Metabolic Networks in Microbes Frontiers in Microbiology
2. Effects of Therapeutic Antibodies on Gene and Protein Signatures in Asthma Patients: A Comparative Systematic Review Biomedicines, Vol. 10, Núm. 2
3. Polymorphisms in Human IL4, IL10, and TNF Genes Are Associated with an Increased Risk of Developing NSAID-Exacerbated Respiratory Disease Genes, Vol. 13, Núm. 4
4. Ten Years of Experience Support Pharmacogenetic Testing to Guide Individualized Drug Therapy Pharmaceutics, Vol. 14, Núm. 1

2021

1. Genetics and Epigenetics of Nasal Polyposis: A Systematic Review Journal of investigational allergology & clinical immunology, Vol. 31, Núm. 3, pp. 196-211
2. IL-5 Receptor Subunit Alpha Expression As A Possible Biomarker In Asthma Journal of Allergy and Clinical Immunology, Vol. 147, Núm. 2, pp. AB245
3. Increased TPSAB1 Copy Number in a Family With Elevated Basal Serum Levels of Tryptase Frontiers in Medicine, Vol. 8
4. PTGDR2 expression in peripheral blood as a potential biomarker in adult patients with asthma Journal of Personalized Medicine, Vol. 11, Núm. 9

2020

1. Atopy can be an interfering factor in genetic association studies of ß-lactam allergy Journal of Investigational Allergology and Clinical Immunology
2. Genetics and epigenetics of atopic dermatitis: An updated systematic review Genes, Vol. 11, Núm. 4
3. Molecular Analysis of IL-5 Receptor Subunit Alpha as a Possible Pharmacogenetic Biomarker in Asthma Frontiers in Medicine, Vol. 7
4. Promoter genotyping and mRNA expression– based analysis of the PTGDR gene in allergy Journal of Investigational Allergology and Clinical Immunology, Vol. 30, Núm. 2, pp. 117-126

2019

1. CRTH2 mRNA levels in peripheral blood of adult patients with nasal polyposis Allergy
2. In vitro silencing of Y-RNA: a potential new tool for studying an epigenetic mechanism recently described in allergy EAACI Congress
3. In vitro silencing of YRNAs, a potential new tool for studying a epigenetic mechanisms recently described in allergy Allergy
4. PTGDR expression is upregulated through retinoic acid receptors (RAR) mechanism in allergy PLoS ONE, Vol. 14, Núm. 4
5. Relationship between CRTH2 mRNA expression in peripheral blood and IgE and eosinophil levels in adult patients with asthma Allergy and immunology
6. YRNAs overexpression and potential implications in allergy World Allergy Organization Journal, Vol. 12, Núm. 8

2018

1. Chromatin immunoprecipitation (ChIP)assays identify a functional retinoic acid receptorbinding site and−549T>C SNP in the PTGDR‐5′region Allergy
2. Cluster Analysis Identifies 3 Phenotypes within Allergic Asthma Journal of Allergy and Clinical Immunology: In Practice, Vol. 6, Núm. 3, pp. 955-961.e1
3. In vitro and in vivo analyses of the PTGDR involvement in allergic asthma andresponse to the treatment with corticosteroids Allergy

2017

1. A Ras GTPase associated protein is involved in the phototropic and circadian photobiology responses in fungi Scientific Reports, Vol. 7
2. Combining multivariate analysis techniques for phenotyping Allergic Asthma CEB 2017: XVI Spanish Biometric Conference
3. PTGDR gene expression and response to dexamethasone treatment in an in vitro model PLoS ONE, Vol. 12, Núm. 10
4. PTGDR influences cytokine levels in theA549 cell line Allergy
5. Pharmacogenetics and the treatment of asthma Pharmacogenomics, Vol. 18, Núm. 13, pp. 1271-1280

2016

1. Analysis of FOXP3 gene in children with allergy and autoimmune diseases Allergologia et Immunopathologia, Vol. 44, Núm. 1, pp. 32-40
2. Applications of molecular genetics to the study of asthma Methods in Molecular Biology (Humana Press Inc.), pp. 1-13
3. Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication Current Biology, Vol. 26, Núm. 12, pp. 1577-1584
4. Filaggrin gene mutations and new SNPs in asthmatic patients: A cross-sectional study in a Spanish population Allergy, Asthma and Clinical Immunology, Vol. 12, Núm. 1
5. Genetic variants modulate the PTGDR expression Allergy
6. Interactions of DNA and proteins: Electrophoretic mobility shift assay in asthma Methods in Molecular Biology (Humana Press Inc.), pp. 91-105
7. Introduction to the gene expression analysis Methods in Molecular Biology (Humana Press Inc.), pp. 29-43
8. Preface Molecular Genetics of Asthma (Humana Press), pp. V-XI
9. Retinoic acid modulates PTGDR promoter activity Journal of Investigational Allergology and Clinical Immunology, Vol. 26, Núm. 4, pp. 249-255
10. Validation of reference genes in mRNA expression analysis applied to the study of asthma Methods in Molecular Biology (Humana Press Inc.), pp. 57-69

2015

1. Fungal cryptochrome with DNA repair activity reveals an early stage in cryptochrome evolution Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Núm. 49, pp. 15130-15135
2. Genetic variants regulate the promoteractivity of PTGDR European Academy of Allergy and Clinical Immunology Congress
3. Genome-wide association studies (GWAS) and their importance in asthma Allergologia et Immunopathologia, Vol. 43, Núm. 6, pp. 601-608
4. Retinoic acid selectively modulated PTGDR expression in A549 lungcarcinoma cell line European Academy of Allergy and Clinical Immunology Congress

2014

1. Genome-wide expression profiling of B lymphocytes reveals IL4R increase in allergic asthma Journal of Allergy and Clinical Immunology, Vol. 134, Núm. 4, pp. 972-975
2. Implications of cytokine genes in allergic asthma Allergologia et Immunopathologia, Vol. 42, Núm. 6, pp. 603-608
3. The -549T>C PTGDR promoterpolymorphism influence the respond todexamethasone administration in theA549 lung cell line Allergy
4. The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases Allergologia et Immunopathologia, Vol. 42, Núm. 1, pp. 64-68

2013

1. Polymorphisms of the IL12B, IL1B, and TNFA genes and susceptibility to asthmaJournal of Investigational Allergology and Clinical Immunology, Vol. 23, Núm. 7, pp. 487-494

2012

1. Genetic association study in nasal polyposis Journal of Investigational Allergology and Clinical Immunology, Vol. 22, Núm. 5, pp. 331-340
2. Haplotypes and diplotypes in thetryptase gene (TPSAB1 gene), a highlypolymorphic gene EAACI Congress of the European Academy of Allergy and Clinical Immunology
3. Modulation of the serum cytokine expression pattern in hymenoptera allergic patients treated with specific venom immunotherapy Open Immunology Journal, Vol. 5, Núm. 1, pp. 13-19
4. The genetics and molecular biology of carotenoid biosynthesis in mucorales Biotechnology of Fungal Genes, pp. 21-52
5. Tryptase: Genetic and functional considerations Allergologia et Immunopathologia, Vol. 40, Núm. 6, pp. 385-389

2011

1. 363C>T polymorphism of TPSAB1 genein allergic patients Allergy
2. Functional analysis of the -95G>T PTGDRpromoter variant in asthmatic patients Allergy
3. Functional analysis of the phycomyces carRA gene encoding the enzymes phytoene synthase and lycopene cyclase PLoS ONE, Vol. 6, Núm. 8
4. PTGDR gene in asthma: A functional, genetic, and epigenetic study Allergy: European Journal of Allergy and Clinical Immunology, Vol. 66, Núm. 12, pp. 1553-1562
5. The TCCTG Haplotype (-613C>T, -549T>C, -441C>T, -197T>C and -95G>T) of PTGDR Gene is Associated with Allergic Sensitization Journal of Allergy and Clinical Immunology, Vol. 127, Núm. 2, pp. AB5-AB5

2010

1. Associacion Of 308G>A And -238G>A TNF-α Polymorphisms With Asthma In A Spanish Population Journal of Allergy and Clinical Immunology, Vol. 125, Núm. 2, pp. AB50
2. Protein-DNA interactions in the promoter region of the Phycomyces carB and carRA genes correlate with the kinetics of their mRNA accumulation in response to light Fungal Genetics and Biology, Vol. 47, Núm. 9, pp. 773-781
3. Study of cross-reactivity between proton pump inhibitors Journal of Investigational Allergology and Clinical Immunology, Vol. 20, Núm. 2, pp. 157-161

2009

1. A new PTGDR promoter polymorphism in a population of children with asthma Pediatric Allergy and Immunology, Vol. 20, Núm. 2, pp. 151-156
2. Case-control study of (CCTTT)n polymor-phism of NOS2A in nasal polyposis Allergy
3. Different effects on pulmonary VEGF expression andseptation in newborn rats with prenataldexamethasone and betamethasone Acta Paediatrica
4. Phycomyces MADB interacts with MADA to form the primary photoreceptor complex for fungal phototropism Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Núm. 17, pp. 7095-7100

2008

1. (CCTTT)n polymorphism of NOS2A in nasal polyposis and asthma: A case-control study Journal of Investigational Allergology and Clinical Immunology, Vol. 18, Núm. 4, pp. 239-244
2. Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma Allergologia et Immunopathologia, Vol. 36, Núm. 5, pp. 259-263
3. Late tolerance to hen’s egg can be amarker of subsequent aeroallergensensitisation Allergy
4. Successful specific venomimmunotherapy is associated with anincrease in serum IL-10 levels Allergy

2007

1. 927T>C CYSLTR1 and –444A>C LTC4S polymorphisms in childrenwith asthma and atopic dermatitis Acta Paediatrica
2. Evaluation of 549T4C, 441C4T and 197T4C promoter polymorphisms ofprostanoid DP receptor (PTGDR) genein a population of Spanish children withasthma Allergy
3. Interacciones genes-ambiente. Epigenética en alergia Allergologia et Immunopathologia
4. Interactions between genes and the environment. Epigenetics in allergy Allergologia et Immunopathologia, Vol. 35, Núm. 6, pp. 254-258
5. Proteomic approaches for identifying new allergens and diagnosing allergic diseases Clinica Chimica Acta, Vol. 385, Núm. 1-2, pp. 21-27
6. Simultaneous hypersensitivity tometronidazole and spiramycin Allergy

2006

1. 927T > C polymorphism of the cysteinyl-leukotriene type-1 receptor (CYSLTR1) gene in children with asthma and atopic dermatitis Pediatric Allergy and Immunology, Vol. 17, Núm. 5, pp. 323-328
2. Analysis of 927T > C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma Journal of Investigational Allergology and Clinical Immunology, Vol. 16, Núm. 6, pp. 331-337
3. Promoter genetic variants of prostanoid DP receptor (PTGDR) gene in patients with asthma Allergy: European Journal of Allergy and Clinical Immunology, Vol. 61, Núm. 5, pp. 543-548
4. The Phycomyces madA gene encodes a blue-light photoreceptor for phototropism and other light responses Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Núm. 12, pp. 4546-4551

2002

1. Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase European Journal of Biochemistry, Vol. 269, Núm. 3, pp. 902-908