Sistema de blogs Diarium
Universidad de Salamanca
Ricardo José Gómez Nieto
Profesor Contratado Doctor
 
Vítor Facultad de Medicina

Publicaciones Científicas

Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model. Díaz-Rodríguez SM, Herrero-Turrión MJ, García-Peral C, Gómez-Nieto R. Frontiers Molecular Neuroscience. 2024 Jan 5;16:1322750. doi: 10.3389/fnmol.2023.1322750.

 

Enhanced Membrane Incorporation of H289Y Mutant GluK1 Receptors from the Audiogenic Seizure-Prone GASH/Sal Model: Functional and Morphological Impacts on Xenopus Oocytes. Díaz-Rodríguez SM, Ivorra I, Espinosa J, Vegar C, Herrero-Turrión MJ, López DE, Gómez-Nieto R, Alberola-Die A. International Journal of Molecular Sciences. 2023 Nov 28;24(23):16852. doi: 10.3390/ijms242316852.

 

The nuclei of the lateral lemniscus: unexpected players in the descending auditory pathway. Gómez-Martínez M, Rincón H, Gómez-Álvarez M, Gómez-Nieto R, Saldaña E. Frontiers in Neuroanatomy. 2023 Aug 9;17:1242245. doi: 10.3389/fnana.2023.1242245.

 

Proteomic and Bioinformatic Tools to Identify Potential Hub Proteins in the Audiogenic Seizure-Prone Hamster GASH/Sal. García-Peral C, Ledesma MM, Herrero-Turrión MJ, Gómez-Nieto R, Castellano O, López DE. Diagnostics (Basel). 2023 Mar 9;13(6):1048. doi: 10.3390/diagnostics13061048.

 

Editorial: Challenges and Conundrums in Cannabinoid-Based Treatments for Epilepsy Syndromes and Associated Neurobehavioral Comorbidities. Gómez-Nieto R, López DE, Garcia-Cairasco N. Frontiers in Behavioral Neuroscience. 2021 Nov 11;15:781852. doi: 10.3389/fnbeh.2021.781852.

 

Distribution of the Cannabinoid Receptor Type 1 in the Brain of the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal. Fuerte-Hortigón A, Gonçalves J, Zeballos L, Masa R, Gómez-Nieto R, López DE. Frontiers in Behavioral Neuroscience. 2021 Mar 24;15:613798. doi: 10.3389/fnbeh.2021.613798.

 

Behavioral and Molecular Effects Induced by Cannabidiol and Valproate Administration in the GASH/Sal Model of Acute Audiogenic Seizures. Cabral-Pereira G, Sánchez-Benito D, Díaz-Rodríguez SM, Gonçalves J, Sancho C, Castellano O, Muñoz LJ, López DE, Gómez-Nieto R. Frontiers in Behavioral Neuroscience. 2021 Jan 22;14:612624. doi: 10.3389/fnbeh.2020.612624.

 

Prepulse Inhibition of the Auditory Startle Reflex Assessment as a Hallmark of Brainstem Sensorimotor Gating Mechanisms. Gómez-Nieto R, Hormigo S, López DE. Brain Science. 2020 Sep 16;10(9):E639. doi: 10.3390/brainsci10090639. 

 

Inferior Colliculus Transcriptome After Status Epilepticus in the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal. Díaz-Rodríguez SM, López-López D, Herrero-Turrión MJ, Gómez-Nieto R, Canal-Alonso A, Lopéz DE. Frontiers in Neuroscience. 2020 May 26;14:508. doi: 10.3389/fnins.2020.00508. 

Morphological and molecular correlates of altered hearing sensitivity in the genetically audiogenic seizure-prone hamster GASH/Sal. Sánchez-Benito D, Hyppolito MA, Alvarez-Morujo AJ, López DE, Gómez-Nieto RHearing Research. 2020 Apr 26;392:107973. doi: 10.1016/j.heares.2020.107973. 

 

Analysis of gene variants in the GASH/Sal model of epilepsy. Díaz-Casado E, Gómez-Nieto R, de Pereda JM, Muñoz LJ, Jara-Acevedo M, López DE. PLoS One. 2020 Mar 13;15(3):e0229953. doi: 10.1371/journal.pone.0229953.

 

Top Common Differentially Expressed Genes in the Epileptogenic Nucleus of Two Strains of Rodents Susceptible to Audiogenic Seizures: WAR and GASH/Sal. Damasceno S, Gómez-Nieto R, Garcia-Cairasco N, Herrero-Turrión MJ, Marín F, Lopéz DE. Frontiers in Neurology. 2020 Feb 13;11:33. doi: 10.3389/fneur.2020.00033. 

 

Molecular tools for the characterization of seizure susceptibility in genetic rodent models of epilepsy. Bosque JR, Gómez-Nieto R, Hormigo S, Herrero-Turrión MJ, Díaz-Casado E, Sancho C, López DE. Epilepsy & Behavior. 2019 Nov 1:106594. doi: 10.1016/j.yebeh.2019.106594. Review.

 

Relations between Sensorimotor Integration and Speech Disorders in Parkinson’s Disease. Millian-Morell L, Lopez-Alburquerque T, Rodriguez-Rodriguez A, Gómez-Nieto R, Carro J, Meilan JJG, Martinez-Sanchez F, Sancho C, Lopez DE. Current Alzheimer Research. 2018;15(2):149-156. doi: 10.2174/1567205014666170829103019.

 

Morphological correlates of sex differences in acoustic startle response and prepulse inhibition through projections from locus coeruleus to cochlear root neurons. Hormigo S, Gómez-Nieto R, Sancho C, Herrero-Turrión J, Carro J, López DE, Horta-Júnior JA. Brain Structure and Function. 2017 Apr 5. doi: 10.1007/s00429-017-1415-1.

 

Morphofunctional alterations in the olivocochlear efferent system of the genetic audiogenic seizure-prone hamster GASH:Sal. Sánchez-Benito D, Gómez-Nieto R, Hernández-Noriega S, Murashima AA, de Oliveira JA, Garcia-Cairasco N, López DE, Hyppolito MA. Epilepsy & Behavior. 2016 Aug 1. pii: S1525-5050(16)30141-X. doi: 10.1016/j.yebeh.2016.05.040.

 

Overexpression of the immediate-early genes Egr1, Egr2, and Egr3 in two strains of rodents susceptible to audiogenic seizures. López-López D, Gómez-Nieto R, Herrero-Turrión MJ, García-Cairasco N, Sánchez-Benito D, Ludeña MD, López DE. Epilepsy & Behavior. 2016 Jan 13. pii: S1525-5050(15)00675-7. doi: 10.1016/j.yebeh.2015.12.020.

 

Sex-Dependent Effects of Prenatal Stress on Learned Helplessness and Anxiety-Related Behaviours in Wistar Rats. Inês Pereira-Figueiredo, Consuelo Sancho, Juan Carro, Dolores E. López, Ricardo Gómez-Nieto, Orlando Castellano. Journal of Behavioral and Brain Science. Vol.5 No.7, July 2015. DOI: 10.4236/jbbs.2015.57026

 

Sex differences in the effects of sertraline and stressors in rats previously exposed to restrain stress. Inês Pereira-Figueiredo, Juan Carro, Luis J. Muñoz, Consuelo Sancho, Orlando Castellano, Ricardo Gómez-Nieto, Dolores E. López. Journal of Biomedical Science and Engineering. Vol.8 No.7, July 2015. DOI: 10.4236/jbise.2015.87038

 

The noradrenergic projection from the locus coeruleus to the cochlear root neurons in rats. Hormigo S, Gómez-Nieto R, Castellano O, Herrero-Turrión MJ, López DE, de Anchieta de Castro E Horta-Júnior J. Brain Structure and Function. 2015;220(3):1477-96. doi: 10.1007/s00429-014-0739-3.

 

A fast cholinergic modulation of the primary acoustic startle circuit in rats. Gómez-Nieto R, Sinex DG, Horta-Júnior J de A, Castellano O, Herrero-Turrión JM, López DE. Brain Structure and Function. 2014 Sep;219(5):1555-73. doi: 10.1007/s00429-013-0585-8.

 

Origin and function of short-latency inputs to the neural substrates underlying the acoustic startle reflex. Gómez-Nieto R, Horta-Júnior Jde A, Castellano O, Millian-Morell L, Rubio ME, López DE. Frontiers in Neuroscience. 2014 Jul 25;8:216. doi: 10.3389/fnins.2014.00216.

 

Chronic administration of risperidone in a rat model of schizophrenia: a behavioural, morphological and molecular study. Castellano O, Arji M, Sancho C, Carro J, Riolobos AS, Molina V, Gómez-Nieto R, de Anchieta de Castro E Horta J Jr, Herrero-Turrión MJ, López DE. Behavioral Brain Research. 2013 Apr 1;242:178-90. doi: 10.1016/j.bbr.2012.12.036.

 

The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Hormigo S, Horta Júnior Jde A, Gómez-Nieto R, López DE. Frontiers in Neural Circuits. 2012 Jun 28;6:41. doi: 10.3389/fncir.2012.00041.

 

Ultrastructure, synaptic organization, and molecular components of bushy cell networks in the anteroventral cochlear nucleus of the rhesus monkey. Gómez-Nieto R, Rubio ME. Neuroscience. 2011 Apr 14;179:188-207. doi: 10.1016/j.neuroscience.2011.01.058.

 

A bushy cell network in the rat ventral cochlear nucleus. Gómez-Nieto R, Rubio ME. Journal Comparative Neurology. 2009 Oct 1;516(4):241-63. doi: 10.1002/cne.22139.

 

Neurochemistry of the afferents to the rat cochlear root nucleus: possible synaptic modulation of the acoustic startle. Gómez-Nieto R, Horta-Junior JA, Castellano O, Herrero-Turrión MJ, Rubio ME, López DE. Neuroscience. 2008 Jun 12;154(1):51-64. doi: 10.1016/j.neuroscience.2008.01.079.

 

Cholinergic input from the ventral nucleus of the trapezoid body to cochlear root neurons in rats. Gómez-Nieto R, Rubio ME, López DE. Journal Comparative Neurology. 2008 Jan 20;506(3):452-68.

 

Capítulos de Libro

 

auditory

Gómez-Nieto R., Horta-Júnior J.A., Castellano O., Sinex D.G., and López D. E.  (2010). “Auditory prepulse inhibition of neuronal activity in the rat cochlear root nucleus” in The Neurophysiological Bases of Auditory Perception, eds E.A. López Poveda, A.R. Palmer, and R. Meddis (NewYork,NY:Springer), 79–90.
doi: 10.1007/978-1-4419-5686-6_8

 

Book Medical Use Cannabis

Willian Lazarini-Lopes, Gabriel Servilha-Menezes, Rui Milton Patrício da Silva-Júnior, Ricardo Gómez-Nieto, Dolores E. López, Norberto Garcia-Cairasco, Chapter 21 – “Genetic models of audiogenic seizures: What they are and how cannabinoids and Cannabis-derived compounds can be used to alleviate their symptoms—An updated narrative“, Editor(s): Victor R. Preedy, Vinood B. Patel, Colin R. Martin, Medicinal Usage of Cannabis and Cannabinoids, Academic Press, 2023, Pages 245-263, ISBN 9780323900362, https://doi.org/10.1016/B978-0-323-90036-2.00032-6.

 

Otras publicaciones (Proceedings)

Programme Book 1st Congress Audiogenic Epilepsy “From Models to the Clinic”. (2014). Gómez-Nieto R, Muñoz L.J, et al. Conference: 1st Congress Audiogenic Epilepsy “From Models to the Clinic”, At Salamanca, Spain, Volume: 1

 

Assisted therapy with horses improves the competences established in the curriculum of child education in a girl with autism spectrum disorder. (2017). Claudia Cid Castaño, Covadonga Alonso Pelegrín and Ricardo Gómez-Nieto.  I Congreso Internacional Intervención Terapéutica Asistida con Animales en Educación y Salud, At Valencia, Volume: 84, 93-112, ISSN-e-1575-9393

 

Título: “Alterations in the olivocochlear efferent system of the epileptic hamster GASH:Sal”. Sánchez-Benito D, Hernández-Noriega S, Hyppolito MA, Castellano O, Sancho C, Muñoz LJ, Batista Murashima AD, García-Cairasco N, Álvarez-Morujo AJ, Gómez-Nieto R, López DE (2017). Revista:  Epilepsia, 58 (Suppl. 5):S92    Clave: A, ISNN: 0013-9580 FI: 3.227. doi: 10.1111/epi.13944

 

Título: “Distribution of CB1 cannabinoid receptors in the model of epilepsy GASH: Sal”. Fuerte A, Masa R, Sánchez-Benito D, Hernández-Noriega S, Gómez-Nieto R, López DE . (2017). Revista:  Epilepsia, 58 (Suppl. 5):S92 .  Clave: A, ISNN: 0013-9580 FI: 3.227. doi: 10.1111/epi.13944

 

Título: “Audiogenic seizures induce changes in the gene expression in the inferior colliculus of two animal models of epilepsy, the WAR and GASH:Sal strains”. López DE, Herrero-Turrión MJ; López-López D, Sánchez-Benito D, Sancho C, Hernández-Noriega S, Castellano O, Muñoz LJ, GarcíaCairasco N, Gómez-Nieto R.  (2017). Revista:  Epilepsia, 58 (Suppl. 5):S175 . Clave: A, ISNN: 0013-9580 FI: 3.227. doi: 10.1111/epi.13944

 

Título: “Downregulation of ADGRV1 gene expression in the inferior colliculus of the genetic audiogenic seizure-prone hamster GASH:Sal”. Alvarez-Morujo de Sande D, López-López D, Herrero-Turrión MJ, Sánchez-Benito D, Hernández-Noriega S, Gómez-Nieto R, Álvarez-Morujo AJ, López DE. (2017). Revista:  Epilepsia, 58 (Suppl. 5):S175 .       Clave: A, ISNN: 0013-9580 FI: 3.227. doi: 10.1111/epi.13944

 

Título: “Repetitive epileptic seizures induce behavioral and activation changes in the hamster GASH:Sal”. Hernández-Noriega S, Sánchez-Benito D, Gómez-Nieto R, Cortes de Oliveira JA, Domínguez-Hernández N, García-Cairasco N, Muñoz LJ, Castellano O, López DE, Sancho C . (2017).  Revista:  Epilepsia, 58 (Suppl. 5):S92. Clave: A, ISNN: 0013-9580 FI: 3.227. doi: 10.1111/epi.13944

 

 

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