Software

NUCwave

• NUCwave is a wavelet-based bioinformatic tool that generates nucleosome occupation maps from sequence reads generated by:
  • Chromatin digestion with micrococcal nuclease (MNase-seq)
  • Chemical cleavage of chromatin (CC-seq)
  • Chromatin inmunoprecipitation (ChIP-seq) and fragmentation by sonication

• NUCwave can process datasets by sequencing protocols:
  • Single-read (SR)
  • Paired-end (PE)

• NUCwave requires only two inputs:
  • The dataset of aligned sequence reads
  • The sequence of the reference genome

• NUCwave is implemented in Python and is distributed under GPLv3 license.